For research use only. Not for therapeutic Use.
PFI-4(CAT: I005387) is a potent, selective, and cell-permeable inhibitor of the BRPF1 bromodomain, with an IC50 of 80 nM. It is widely used in epigenetic research to investigate the role of BRPF1 in chromatin remodeling and gene regulation. By specifically targeting the bromodomain of BRPF1, PFI-4 helps elucidate its function in histone acetylation and transcriptional activation, particularly in the context of developmental biology and disease states. Its high specificity and cell permeability make it an invaluable tool for preclinical studies aimed at understanding bromodomain biology and developing targeted epigenetic therapies.
| Catalog Number | I005387 |
| CAS Number | 900305-37-5 |
| Synonyms | N-(1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methoxybenzamide |
| Molecular Formula | C21H24N4O3 |
| Purity | ≥95% |
| Target | Epigenetic Reader Domain |
| Solubility | DMSO: ≤ 26 mg/mL |
| Storage | Store at -20C |
| IC50 | 80 nM |
| InChIKey | QCIJLRJBZDBVDB-UHFFFAOYSA-N |
