For research use only. Not for therapeutic Use.
PFI-653 (Vanin-1-IN-1) is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation[1].
| Catalog Number | I018008 |
| CAS Number | 2173134-00-2 |
| Synonyms | 8-oxa-2-azaspiro[4.5]decan-2-yl-[2-(pyrazin-2-ylmethylamino)pyrimidin-5-yl]methanone |
| Molecular Formula | C18H22N6O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H22N6O2/c25-16(24-6-1-18(13-24)2-7-26-8-3-18)14-9-21-17(22-10-14)23-12-15-11-19-4-5-20-15/h4-5,9-11H,1-3,6-8,12-13H2,(H,21,22,23) |
| InChIKey | VGRLXWFIXGZRMS-UHFFFAOYSA-N |
| SMILES | C1CN(CC12CCOCC2)C(=O)C3=CN=C(N=C3)NCC4=NC=CN=C4 |
| Reference | [1]. Agustin Casimiro-Garcia, et al. Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme. WO2018011681A1. |
