PFK-158

• CAT Number: I001771
• CAS Number: 1462249-75-7
• Molecular Formula: C18H11F3N2O
• Molecular Weight: 328.29
• Purity: ≥95%
• Target: Apoptosis
• Solubility: DMSO: ≥ 30 mg/mL
• Storage: -20°C
• IUPAC Name: (E)-1-pyridin-4-yl-3-[7-(trifluoromethyl)quinolin-2-yl]prop-2-en-1-one
• InChI: 1S/C18H11F3N2O/c19-18(20,21)14-3-1-12-2-4-15(23-16(12)11-14)5-6-17(24)13-7-9-22-10-8-13/h1-11H/b6-5+
• InChIKey: IAJOMYABKVAZCN-AATRIKPKSA-N
• SMILES: C1=CC(=CC2=C1C=CC(=N2)/C=C/C(=O)C3=CC=NC=C3)C(F)(F)F

PFK-158 (Cat.No:I001771) is a small molecule inhibitor that targets phosphofructokinase-1 (PFK-1), a key enzyme involved in glycolysis. By inhibiting PFK-1, PFK-158 disrupts the metabolic pathways of cancer cells, leading to energy depletion and impaired tumor growth. It shows promise as a potential anticancer therapy and is currently being investigated in preclinical studies.