PG 34

• CAT Number: I042884
• CAS Number: 1681056-62-1
• Molecular Formula: C28H25N3O5S2
• Molecular Weight: 547.65
• Purity: ≥95%
• Synonyms: (2R)-N-(furan-2-ylmethyl)-2-[(2-oxo-1H-quinolin-6-yl)sulfonylamino]-3-phenyl-N-(thiophen-2-ylmethyl)propanamide
• InChI: InChI=1S/C28H25N3O5S2/c32-27-13-10-21-17-24(11-12-25(21)29-27)38(34,35)30-26(16-20-6-2-1-3-7-20)28(33)31(18-22-8-4-14-36-22)19-23-9-5-15-37-23/h1-15,17,26,30H,16,18-19H2,(H,29,32)/t26-/m1/s1
• InChIKey: ICLUPJSFAFLDLR-AREMUKBSSA-N
• SMILES: C1=CC=C(C=C1)C[C@H](C(=O)N(CC2=CC=CO2)CC3=CC=CS3)NS(=O)(=O)C4=CC5=C(C=C4)NC(=O)C=C5

PG 34（Cat No.:I042884）is a synthetic compound that acts as a potent inhibitor of various kinases, including those involved in cancer cell growth and proliferation. It specifically targets signaling pathways related to cell cycle regulation, apoptosis, and tumor progression. PG 34 has demonstrated potential as an anticancer agent, particularly in the treatment of solid tumors, by blocking key molecular interactions that enable cancer cells to survive and proliferate. Research into its pharmacodynamics and therapeutic efficacy is ongoing, with hopes of developing it into a viable treatment for various malignancies.

Reference

[1]. Rodrigo F Ortiz-Meoz, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.
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