For research use only. Not for therapeutic Use.
Prostaglandin D<sub>2</sub> (PGD<sub>2</sub>) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD<sub>2</sub> with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD<sub>2</sub>.
| Catalog Number | R056270 |
| CAS Number | 133161-96-3 |
| Synonyms | (1R,2R,3S,5S)-2-[(2Z)-4-Carboxy-2-buten-1-yl]-3,5-dihydroxy-γ-oxocyclopentanehexanoic Acid; (1R,2R,3S,5S)-2-[(2Z)-4-Carboxy-2-butenyl]-3,5-dihydroxy-?γ-oxocyclopentanehexanoic Acid; |
| Molecular Formula | C16H24O7 |
| Purity | ≥95% |
| Target | Prostaglandin Receptor |
| Storage | -80°C |
| IUPAC Name | 6-[(1R,2R,3S,5S)-2-[(Z)-4-carboxybut-2-enyl]-3,5-dihydroxycyclopentyl]-4-oxohexanoic acid |
| InChI | InChI=1S/C16H24O7/c17-10(6-8-16(22)23)5-7-12-11(13(18)9-14(12)19)3-1-2-4-15(20)21/h1-2,11-14,18-19H,3-9H2,(H,20,21)(H,22,23)/b2-1-/t11-,12-,13+,14+/m1/s1 |
| InChIKey | XSGSZQDCVYMZGQ-YQQXMBKZSA-N |
| SMILES | C1C(C(C(C1O)CC=CCC(=O)O)CCC(=O)CCC(=O)O)O |
