PGE-M

• CAT Number: R047506
• CAS Number: 24769-56-0
• Molecular Formula: C16H24O7
• Molecular Weight: 328.41
• Purity: ≥95%
• Synonyms: (1R,2R,5R)-2-(2-Carboxyethyl)-5-hydroxy-ε,3-dioxocyclopentaneoctanoic Acid; (-)-7α-Hydroxy-5,11-diketotetranorprostan-1,16-dioic Acid; (-)-PGE2UM; 7-Hydroxy-5,11-diketotetranorprosta-1,16-dioic Acid; PGE2UM
• Target: Endogenous Metabolite
• Storage: -80°C
• InChIKey: ZJAZCYLYLVCSNH-JHJVBQTASA-N

PGE-M(CAT: R047506), or Prostaglandin E Metabolite, is a major urinary metabolite of Prostaglandin E2 (PGE2), which plays a critical role in inflammation, pain, and fever responses. PGE-M is commonly measured in urine as a biomarker for PGE2 synthesis and is often used in research to assess inflammation and cancer progression, particularly in colorectal cancer. Monitoring PGE-M levels can provide insights into the effectiveness of anti-inflammatory drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs), and their impact on prostaglandin pathways.