For research use only. Not for therapeutic Use.
PGL-135 is a Polyglutamine Aggregation Inhibitor
Catalog Number | I034553 |
CAS Number | 26278-83-1 |
Synonyms | PGL-135; PGL135; PGL 135 |
Molecular Formula | C9H10N2OS |
Purity | 98% |
Solubility | To be determined |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 2-Amino-4,7-dimethyl-6-benzothiazolol |
InChI | InChI=1S/C9H10N2OS/c1-4-3-6(12)5(2)8-7(4)11-9(10)13-8/h3,12H,1-2H3,(H2,10,11) |
InChIKey | RUTNKAMSWIPHJW-UHFFFAOYSA-N |
SMILES | OC1=CC(C)=C2N=C(N)SC2=C1C |
Reference | 1: Hockly E, Tse J, Barker AL, Moolman DL, Beunard JL, Revington AP, Holt K, Sunshine S, Moffitt H, Sathasivam K, Woodman B, Wanker EE, Lowden PA, Bates GP. Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington’s disease. Neurobiol Dis. 2006 Jan;21(1):228-36. doi: 10.1016/j.nbd.2005.07.007. Epub 2005 Aug 18. PMID: 16111888. |