For research use only. Not for therapeutic Use.
PGN36 (Compound 18) is a selective cannabinoid CB2 receptor (CB2R) antagonist with a Ki of 0.09 µM[1].
Catalog Number | I043687 |
CAS Number | 1564253-75-3 |
Synonyms | 1-benzyl-3-(cyclohexylmethoxy)-5-nitroindazole |
Molecular Formula | C21H23N3O3 |
Purity | ≥95% |
InChI | InChI=1S/C21H23N3O3/c25-24(26)18-11-12-20-19(13-18)21(27-15-17-9-5-2-6-10-17)22-23(20)14-16-7-3-1-4-8-16/h1,3-4,7-8,11-13,17H,2,5-6,9-10,14-15H2 |
InChIKey | VLMJWSVJQMZYSE-UHFFFAOYSA-N |
SMILES | C1CCC(CC1)COC2=NN(C3=C2C=C(C=C3)[N+](=O)[O-])CC4=CC=CC=C4 |
Reference | [1]. González-Naranjo P, et al. New cannabinoid receptor antagonists as pharmacological tool. Bioorg Med Chem. 2020 Oct 1;28(19):115672. |