Phenacetin

• CAT Number: A000326
• CAS Number: 62-44-2
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.22
• Purity: ≥95%
• Synonyms: Acetophenetidin
• Target: COX
• Solubility: Soluble in DMSO > 10 mM
• Storage: 3 years -20C powder
• IUPAC Name: N-(4-ethoxyphenyl)acetamide
• InChI: InChI=1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
• InChIKey: CPJSUEIXXCENMM-UHFFFAOYSA-N
• SMILES: CCOC1=CC=C(C=C1)NC(=O)C

Phenacetin（Cat No.:A000326）is an analgesic and antipyretic once widely used to relieve pain and reduce fever. It functions by inhibiting prostaglandin synthesis, thus alleviating inflammation and pain. Although effective, Phenacetin was linked to serious side effects, including kidney damage, anemia, and carcinogenic risks, leading to its withdrawal from the market in many countries. Historically, it was a common component in over-the-counter pain remedies. Modern alternatives with safer profiles have largely replaced Phenacetin, but its legacy highlights the importance of rigorous drug safety evaluations and monitoring in pharmacology.