Phenamil

• CAT Number: I034576
• CAS Number: 2038-35-9
• Molecular Formula: C12H12ClN7O
• Molecular Weight: 305.726
• Purity: 98%
• Synonyms: Phenamil
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazinecarboxamide
• InChI: InChI=1S/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21)
• InChIKey: NIOHELZQFBGCEO-UHFFFAOYSA-N
• SMILES: ClC1=C(N)N=C(N)C(C(NC(NC2=CC=CC=C2)=N)=O)=N1

Phenamil is an irreversible inhibitor of amiloride-sensitive Na channels; derivative of amiloride, synergizing bone formation with BMP2 and inhibits BMP2 induced cyst-like bone formation.

Reference

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