Phenethicillin sodium

• CAT Number: R042572
• CAS Number: 30302-52-4
• Molecular Formula: C17H19N2NaO5S
• Molecular Weight: 386.40
• Purity: ≥95%
• Synonyms: sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxypropanoylamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• InChI: InChI=1S/C17H20N2O5S.Na/c1-9(24-10-7-5-4-6-8-10)13(20)18-11-14(21)19-12(16(22)23)17(2,3)25-15(11)19;/h4-9,11-12,15H,1-3H3,(H,18,20)(H,22,23);/q;+1/p-1/t9?,11-,12+,15-;/m1./s1
• InChIKey: HZRQUJWXQAEVBK-DVLYDCSHSA-M
• SMILES: CC(C(=O)NC1C2N(C1=O)C(C(S2)(C)C)C(=O)[O-])OC3=CC=CC=C3.[Na+]

Phenethicillin Sodium(CAT: R042572) is a β-lactam antibiotic belonging to the penicillin class, structurally similar to penicillin V. It is effective against Gram-positive bacteria by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Phenethicillin sodium is acid-stable, making it suitable for oral administration. Though largely replaced by more modern antibiotics in clinical use, it remains relevant in microbiological research and antibiotic susceptibility studies. Its sodium salt form enhances solubility, facilitating in vitro experimentation. Phenethicillin sodium serves as a useful reference compound in studies involving β-lactam resistance mechanisms and penicillin-binding protein interactions.