For research use only. Not for therapeutic Use.
Phenothrin（Cat No.:I002886）is a synthetic pyrethroid insecticide widely used for controlling lice, fleas, and other household pests. It functions by targeting the nervous system of insects, disrupting sodium channel activity, and causing paralysis and eventual death. Phenothrin is favored for its high efficacy, low mammalian toxicity, and rapid action. Commonly found in shampoos, sprays, and environmental treatments, it is effective against adult insects but may require combination therapies for comprehensive pest control, including eggs and larvae. Its safety and versatility make it a key tool in public health and pest management.
| Catalog Number | I002886 |
| CAS Number | 26002-80-2 |
| Molecular Formula | C23H26O3 |
| Purity | ≥95% |
| Target | Parasite |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | (3-phenoxyphenyl)methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate |
| InChI | InChI=1S/C23H26O3/c1-16(2)13-20-21(23(20,3)4)22(24)25-15-17-9-8-12-19(14-17)26-18-10-6-5-7-11-18/h5-14,20-21H,15H2,1-4H3 |
| InChIKey | SBNFWQZLDJGRLK-UHFFFAOYSA-N |
| SMILES | CC(=CC1C(C1(C)C)C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C |
| Reference | </br>1:Topical phenothrin treatment in a case of crusted scabies with nail involvement. Taniguchi H, Matsuo N, Ohtaki N.J Dermatol. 2017 Apr;44(4):e64-e65. doi: 10.1111/1346-8138.13626. Epub 2016 Sep 26. No abstract available. PMID: 27666132 </br>2:Evaluation of the genotoxicity of the pyrethroid insecticide phenothrin. Nagy K, Rácz G, Matsumoto T, Ádány R, Ádám B.Mutat Res Genet Toxicol Environ Mutagen. 2014 Aug;770:1-5. doi: 10.1016/j.mrgentox.2014.05.001. Epub 2014 May 14. PMID: 25344157 </br>3:Comparison of phenothrin mousse, phenothrin lotion, and wet-combing for treatment of head louse infestation in the UK: a pragmatic randomised, controlled, assessor blind trial. Burgess IF, Brown CM, Nair P.F1000Res. 2014 Jul 10;3:158. doi: 10.12688/f1000research.2026.1. eCollection 2014. PMID: 25254106 Free PMC Article</br>4:d-Phenothrin-induced oxidative DNA damage in rat liver and kidney determined by HPLC-ECD/DAD. Atmaca E, Aksoy A.Environ Toxicol. 2015 May;30(5):607-13. doi: 10.1002/tox.21938. Epub 2013 Dec 12. PMID: 24339023 </br>5:Kinetic and product study of the heterogeneous reactions of NO3 radicals with suspended resmethrin, phenothrin, and fenvalerate particles. Wang Y, Zhang P, Yang B, Liu C, Shu J.Chemosphere. 2013 Jan;90(2):848-55. doi: 10.1016/j.chemosphere.2012.09.096. Epub 2012 Oct 24. PMID: 23102722 </br>6:Photoinduced oxidation of the insecticide phenothrin on soil surfaces. Suzuki Y, Lopez A, Ponte M, Fujisawa T, Ruzo LO, Katagi T.J Agric Food Chem. 2011 Sep 28;59(18):10182-90. doi: 10.1021/jf202564c. Epub 2011 Sep 6. PMID: 21877720 </br>7:Toxicity of the mosquito control insecticide phenothrin to three life stages of the grass shrimp (Palaemonetes pugio). Key PB, Chung KW, Hoguet J, Sapozhnikova Y, Delorenzo ME.J Environ Sci Health B. 2011;46(5):426-31. doi: 10.1080/10934529.2011.549409. PMID: 21614717 </br>8:Residual efficacy of field-applied permethrin, d-phenothrin, and resmethrin on plant foliage against adult mosquitoes. Amoo AO, Xue RD, Qualls WA, Quinn BP, Bernier UR.J Am Mosq Control Assoc. 2008 Dec;24(4):543-9. PMID: 19181063 </br>9:Toxicity of delta-phenothrin and resmethrin to non-target insects. Antwi FB, Peterson RK.Pest Manag Sci. 2009 Mar;65(3):300-5. doi: 10.1002/ps.1688. PMID: 19097021 </br>10:Burns and Phenothrin anti-lice lotion. Evans L, Agarwal R, Dickson WA, Drew PJ.Burns. 2004 Sep;30(6):616. No abstract available. Erratum in: Burns. 2005 Mar;31(2):254. PMID: 15302436 |
