A phentolamine-d4 hydrochloride（Cat No.:S000543） is a deuterated form of phentolamine hydrochloride, where four hydrogen atoms are replaced with deuterium. Phentolamine is a non-selective alpha-adrenergic antagonist used to treat hypertension and manage pheochromocytoma-related hypertensive episodes. It is also used during diagnostic tests for pheochromocytoma. The introduction of deuterium in phentolamine-d4 hydrochloride enhances its metabolic stability, providing a useful tool for pharmacokinetic and metabolic studies.
| Catalog Number | S000543 |
| CAS Number | 1346599-65-2 |
| Molecular Formula | C17H16D4ClN3O |
| Purity | ≥95% |
| IUPAC Name | 3-[4-methyl-N-[(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)methyl]anilino]phenol;hydrochloride |
| InChI | InChI=1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H/i9D2,10D2; |
| InChIKey | TUEJFGFQYKDAPM-PQDNHERISA-N |
| SMILES | CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.Cl |
