Phenylbutazone(diphenyl-d10)

• CAT Number: S000186
• CAS Number: 1219794-69-0
• Molecular Formula: C19H10D10N2O2
• Molecular Weight: 318.44
• Purity: ≥95%
• Target: COX
• IUPAC Name: 4-butyl-1,2-bis(2,3,4,5,6-pentadeuteriophenyl)pyrazolidine-3,5-dione
• InChI: InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3/i4D,5D,6D,7D,8D,9D,10D,11D,12D,13D
• InChIKey: VYMDGNCVAMGZFE-MIPJZDBJSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])N2C(=O)C(C(=O)N2C3=C(C(=C(C(=C3[2H])[2H])[2H])[2H])[2H])CCCC)[2H])[2H]

Phenylbutazone(diphenyl-d10) (CAS: 1219794-69-0), a premium pharmaceutical research compound designed for advanced anti-inflammatory and analgesic studies. As a deuterated analog of Phenylbutazone, it offers enhanced stability and improved pharmacokinetic properties. Phenylbutazone(diphenyl-d10) is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for pain management and inflammatory conditions. Trusted by leading laboratories, Phenylbutazone(diphenyl-d10) is your go-to solution for cutting-edge anti-inflammatory research. Unlock new possibilities in pain and inflammation treatment with Phenylbutazone(diphenyl-d10), where innovation meets reliability.

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. G A Reed, et al. Inactivation of prostaglandin H synthase and prostacyclin synthase by phenylbutazone. Requirement for peroxidative metabolism. Mol Pharmacol. 1985 Jan;27(1):109-14.
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[3]. Guiying Chen, et al. Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy. Sci Rep. 2016 Apr 29;6:25317.
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[4]. Beretta C, et al. COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. Pharmacol Res. 2005 Oct;52(4):302-6.
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