Phenylethynsulfonic Acid Amide

For research use only. Not for therapeutic Use.

  • CAT Number: R005973
  • CAS Number: 64984-31-2
  • Molecular Formula: C8H7NO2S
  • Molecular Weight: 181.21
  • Purity: ≥95%
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Semapimod HCl (Cat No.: R005973) is a selective inhibitor of the enzyme sphingosine kinase 1 (SK1), which is involved in the production of sphingosine-1-phosphate (S1P), a bioactive lipid signaling molecule. By inhibiting SK1, Semapimod reduces S1P levels, impacting various cellular processes such as immune cell migration, inflammation, and cancer cell proliferation. It has been studied for its potential to treat conditions like autoimmune diseases, cancer, and inflammation. Ongoing research aims to evaluate its therapeutic efficacy and safety in clinical settings.


CAS Number 64984-31-2
Synonyms

Phenyl-ethynesulfonic Acid Amide; Pifithrin-υ; PFTυ;

Molecular Formula C8H7NO2S
Purity ≥95%
Target Metabolic Enzyme/Protease
Solubility Soluble in DMSO > 10 mM
Storage Store at 4°C
IUPAC Name 2-phenylethynesulfonamide
InChI InChI=1S/C8H7NO2S/c9-12(10,11)7-6-8-4-2-1-3-5-8/h1-5H,(H2,9,10,11)
InChIKey ZZUZYEMRHCMVTB-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)C#CS(=O)(=O)N

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