Phenytoin Sodium

• CAT Number: A000757
• CAS Number: 630-93-3
• Molecular Formula: C15H11N2NaO2
• Molecular Weight: 274.25
• Purity: ≥95%
• Synonyms: 630-93-3; Dilantin sodium; Diphenylhydantoin Sodium; Diphantoine; Fenidantoin
• Target: Sodium Channel
• Solubility: >11.6mg/mL in DMSO
• Storage: -20°C
• InChI: 1S/C15H12N2O2.Na/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12;/h1-10H,(H2,16,17,18,19);/q;+1/p-1
• InChIKey: FJPYVLNWWICYDW-UHFFFAOYSA-M
• SMILES: C1=CC=C(C=C1)C2(C(=O)[N-]C(=O)N2)C3=CC=CC=C3.[Na+]

Phenytoin Sodium is a potent K+ channel block. It also is a potent multi-channel blockers, blocking Na+ and Ca 2+ channels. It selectively blocks persistent INaP over shorter INaP actions and blocks high frequency repetitive firing of action potentials. Phenytoin Sodium is an anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization.

Reference

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