Phillygenin

• CAT Number: I003719
• CAS Number: 487-39-8
• Molecular Formula: C21H24O6
• Molecular Weight: 372.41
• Purity: ≥95%
• Solubility: Soluble to 33 mg/mL in CDCL3
• Storage: 3 years -20C powder

Phillygenin (CAT: I003719) emerges as a potent and versatile active ingredient derived from Forsythia, a plant with notable medicinal properties. Phillygenin exhibits a range of beneficial effects, including antioxidant properties that counteract oxidative stress, the ability to reduce blood lipid levels, and the inhibition of low-density lipoprotein (LDL) oxidation, a process implicated in atherosclerosis. Moreover, in vitro studies demonstrate Phillygenin’s remarkable potential as an anti-cancer agent, with greater inhibition of mouse B16 melanoma cell growth compared to vincristine, a known chemotherapeutic agent.

Reference

[1]. Ye LH et al. Determination of phillygenin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Eur J Drug Metab Pharmacokinet, 2013 Sep, 38(3):201-7.

[2]. Song W et al. Interaction between phillygenin and human serum albumin based on spectroscopic and molecular docking. Spectrochim Acta A Mol Biomol Spectrosc, 2012 Jan, 85(1):120-6.