For research use only. Not for therapeutic Use.
Phorbol 13-acetate, also known as phorbol-13-myristate acetate (PMA), is a potent tumor promoter derived from the seed oil of the croton plant (Croton tiglium). This compound activates protein kinase C (PKC) and other signal transduction pathways, influencing cell growth, differentiation, and apoptosis. Phorbol 13-acetate is widely used in biomedical research to study cellular processes and as a tool to induce differentiation or activation of immune cells in vitro. Its role in cancer research provides insights into cellular mechanisms and potential therapeutic targets.
| CAS Number | 32752-29-7 |
| Molecular Formula | C22H30O7 |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C22H30O7/c1-10-6-15-20(27,17(10)25)8-13(9-23)7-14-16-19(4,5)22(16,29-12(3)24)18(26)11(2)21(14,15)28/h6-7,11,14-16,18,23,26-28H,8-9H2,1-5H3/t11-,14+,15-,16-,18-,20-,21-,22-/m1/s1 |
| InChIKey | SDSVJYOOAPRSDA-RPCQODIISA-N |
| SMILES | CC1C(C2(C(C2(C)C)C3C1(C4C=C(C(=O)C4(CC(=C3)CO)O)C)O)OC(=O)C)O |
