For research use only. Not for therapeutic Use.
Phosphatidylcholine transfer protein inhibitor-2 (PCTP inhibitor-2) (Cat No.: I040171) is a small molecule that selectively inhibits phosphatidylcholine transfer protein (PCTP), an enzyme involved in the transport of phosphatidylcholine between cellular membranes. By inhibiting PCTP, this compound can alter lipid metabolism and membrane composition, which may have therapeutic potential in conditions related to lipid dysregulation, such as cardiovascular diseases and metabolic disorders. PCTP inhibitor-2 is being studied for its ability to modulate lipid homeostasis and its implications in drug development for metabolic diseases.
| CAS Number | 379712-59-1 |
| Synonyms | N-[[2-chloro-5-[(3-chlorophenyl)sulfamoyl]phenyl]carbamothioyl]-4-fluorobenzamide |
| Molecular Formula | C20H14Cl2FN3O3S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H14Cl2FN3O3S2/c21-13-2-1-3-15(10-13)26-31(28,29)16-8-9-17(22)18(11-16)24-20(30)25-19(27)12-4-6-14(23)7-5-12/h1-11,26H,(H2,24,25,27,30) |
| InChIKey | PLUIJIKIACMFSD-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)Cl)NS(=O)(=O)C2=CC(=C(C=C2)Cl)NC(=S)NC(=O)C3=CC=C(C=C3)F |
| Reference | [1]. Cohen, et al. Preparation of N-benzoyl-N-phenylthiourea and -urea derivatives as phosphatidylcholine transfer protein inhibitors. WO2011022393 |
