For research use only. Not for therapeutic Use.
Calcium ethanolamine phosphate (Cat No.:I008754), also known as ethanolamine phosphate or calcium EAP, is an important component of human cell membrane structure. Calcium ethanolamine phosphate is mainly used as a biochemical reagent. Its agarose complex is the medium of affinity chromatography, and it is also a component of phosphatidylethanolamine, the most abundant phospholipid in animal and plant cell membranes, which is the polar head of its phospholipid molecules.
| Catalog Number | I008754 |
| CAS Number | 10389-08-9 (calcium) |
| Synonyms | Phosphoethanolamine calcium; Calcium 2-aminoethylphosphate, Ca-AEP or Ca-2AEP; calcium EAP; Phosphorylcolamine calcium; Colamine phosphate; Ethanolamine phosphate;Calcium 2-aminoethyl phosphate |
| Molecular Formula | C2H6CaNO4P |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| IUPAC Name | calcium;2-aminoethyl phosphate |
| InChI | InChI=1S/C2H8NO4P.Ca/c3-1-2-7-8(4,5)6;/h1-3H2,(H2,4,5,6);/q;+2/p-2 |
| InChIKey | SYLKQIHLJRQWAY-UHFFFAOYSA-L |
| SMILES | C(COP(=O)([O-])[O-])N.[Ca+2] |
| Reference | </br>1:Comparative analyses of isoforms of the calcium-independent phosphatidylethanolamine N-acyltransferase PLAAT-1 in humans and mice. Hussain Z, Uyama T, Kawai K, Rahman IA, Tsuboi K, Araki N, Ueda N.J Lipid Res. 2016 Nov;57(11):2051-2060. Epub 2016 Sep 13. PMID: 27623847 </br>2:A calcium-dependent acyltransferase that produces N-acyl phosphatidylethanolamines. Ogura Y, Parsons WH, Kamat SS, Cravatt BF.Nat Chem Biol. 2016 Sep;12(9):669-71. doi: 10.1038/nchembio.2127. Epub 2016 Jul 11. PMID: 27399000 Free PMC Article</br>3:Membrane binding of Neuronal Calcium Sensor-1 (NCS1). Lemire S, Jeromin A, Boisselier É.Colloids Surf B Biointerfaces. 2016 Mar 1;139:138-47. doi: 10.1016/j.colsurfb.2015.11.065. Epub 2015 Dec 9. PMID: 26705828 </br>4:Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy. Paran CW, Zou K, Ferrara PJ, Song H, Turk J, Funai K.Biochim Biophys Acta. 2015 Dec;1851(12):1530-8. doi: 10.1016/j.bbalip.2015.09.001. Epub 2015 Sep 8. PMID: 26361872 Free PMC Article</br>5:Surface modification of tri-calcium phosphate nanoparticles by DOPE and/or anti-E6 antibody to enhance uptake of antisense of E6 mRNA. Jebali A, Kalantar SM, Hekmatimoghaddam S, Saffarzadeh N, Sheikha MH, Ghasemi N.Colloids Surf B Biointerfaces. 2015 Feb 1;126:297-302. doi: 10.1016/j.colsurfb.2014.12.040. Epub 2015 Jan 3. PMID: 25601794 </br>6:Calcium-mediated binding of DNA to 1,2-distearoyl-sn-glycero-3-phosphocholine-containing mixed lipid monolayers. Dabkowska AP, Barlow DJ, Clifton LA, Hughes AV, Webster JR, Green RJ, Quinn PJ, Lawrence MJ.Soft Matter. 2014 Mar 21;10(11):1685-95. doi: 10.1039/c3sm52747f. PMID: 24652078 </br>7:Phospholipid mediated activation of calcium dependent protein kinase 1 (CaCDPK1) from chickpea: a new paradigm of regulation. Dixit AK, Jayabaskaran C.PLoS One. 2012;7(12):e51591. doi: 10.1371/journal.pone.0051591. Epub 2012 Dec 20. PMID: 23284721 Free PMC Article</br>8:Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS.Nature. 2011 May 26;473(7348):528-31. doi: 10.1038/nature09968. Epub 2011 May 1. PMID: 21532591 Free PMC Article</br>9:The interactions between cholesterol and phospholipids located in the inner leaflet of human erythrocytes membrane (DPPE and DPPS) in binary and ternary films–the effect of sodium and calcium ions. Wydro P.Colloids Surf B Biointerfaces. 2011 Jan 1;82(1):209-16. doi: 10.1016/j.colsurfb.2010.08.041. Epub 2010 Sep 22. PMID: 20864321 </br>10:Calcium-induced formation of subdomains in phosphatidylethanolamine-phosphatidylglycerol bilayers: a combined DSC, 31P NMR, and AFM study. Picas L, Montero MT, Morros A, Cabañas ME, Seantier B, Milhiet PE, Hernández-Borrell J.J Phys Chem B. 2009 Apr 9;113(14):4648-55. doi: 10.1021/jp8102468. PMID: 19338364 |
