Phosphorous Acid

For research use only. Not for therapeutic Use.

  • CAT Number: R014952
  • CAS Number: 13598-36-2
  • Molecular Formula: H3O3P
  • Molecular Weight: 82
  • Purity: ≥95%
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Phosphorous Acid (Cat.No:R014952) is used as an intermediate in the preparation of other phosphorus compounds. It may be used as one of the reaction components for the synthesis of the following: α-aminomethylphosphonic acids via Mannich-Type Multicomponent Reaction, 1-aminoalkanephosphonic acids via amidoalkylation followed by hydrolysis and N-protected α-aminophosphonic acids (phospho-isosteres of natural amino acids) via amidoalkylation reaction.


Catalog Number R014952
CAS Number 13598-36-2
Synonyms

Phosphonic Acid; Dihydroxyphosphine Oxide

Molecular Formula H3O3P
Purity ≥95%
Storage -20°C
IUPAC Name phosphonic acid
InChI InChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3)
InChIKey ABLZXFCXXLZCGV-UHFFFAOYSA-N
SMILES OP(=O)O
Reference

<span style=”color:#000000;”><span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”>1.<span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>Moedritzer, Kurt, and Riyad R. Irani. &quot;The direct synthesis of &alpha;-aminomethylphosphonic acids. Mannich-type reactions with orthophosphorous acid.&quot;&nbsp;</span><i style=”font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>The Journal of organic chemistry</i><span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>&nbsp;31.5 (1966): 1603-1607.<br />
2.</span><span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>Vinyukov, A. V., M. E. Dmitriev, and V. V. Ragulin. &quot;Amidoalkylation of phosphorous acid.&quot;&nbsp;</span><i style=”font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>Russian Journal of General Chemistry</i><span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>&nbsp;85.2 (2015): 366-369.<br />
3.Amidoalkylation of phosphorous acid. Oleksyszyn J and Gruszeckae. Tetsu to Hagane 22(36), 3537-3540, (1981)</span></span></span></span>

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