For research use only. Not for therapeutic Use.
Phosphorous Acid (Cat.No:R014952) is used as an intermediate in the preparation of other phosphorus compounds. It may be used as one of the reaction components for the synthesis of the following: α-aminomethylphosphonic acids via Mannich-Type Multicomponent Reaction, 1-aminoalkanephosphonic acids via amidoalkylation followed by hydrolysis and N-protected α-aminophosphonic acids (phospho-isosteres of natural amino acids) via amidoalkylation reaction.
Catalog Number | R014952 |
CAS Number | 13598-36-2 |
Synonyms | Phosphonic Acid; Dihydroxyphosphine Oxide |
Molecular Formula | H3O3P |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | phosphonic acid |
InChI | InChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3) |
InChIKey | ABLZXFCXXLZCGV-UHFFFAOYSA-N |
SMILES | OP(=O)O |
Reference | <span style=”color:#000000;”><span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”>1.<span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>Moedritzer, Kurt, and Riyad R. Irani. "The direct synthesis of α-aminomethylphosphonic acids. Mannich-type reactions with orthophosphorous acid." </span><i style=”font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>The Journal of organic chemistry</i><span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”> 31.5 (1966): 1603-1607.<br /> |