Phox-I2

• CAT Number: I012295
• CAS Number: 353495-22-4
• Molecular Formula: C18H15N3O4
• Molecular Weight: 337.335
• Purity: ≥95%
• Synonyms: 3a,​4,​5,​9b-​Tetrahydro-​8-​nitro-​4-​(3-​nitrophenyl)​-3H-​Cyclopenta[c]​quinoline
• Target: NF-κB
• IUPAC Name: 8-nitro-4-(3-nitrophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
• InChI: InChI=1S/C18H15N3O4/c22-20(23)12-4-1-3-11(9-12)18-15-6-2-5-14(15)16-10-13(21(24)25)7-8-17(16)19-18/h1-5,7-10,14-15,18-19H,6H2
• InChIKey: PADQUVZDTGNTLH-UHFFFAOYSA-N
• SMILES: C1C=CC2C1C(NC3=C2C=C(C=C3)[N+](=O)[O-])C4=CC(=CC=C4)[N+](=O)[O-]

Phox-I2 (Cat.No:I012295) is a chemical compound that functions as a potent inhibitor of NADPH oxidase, an enzyme responsible for generating reactive oxygen species (ROS). Phox-I2 has shown potential in attenuating oxidative stress and inflammation. Its inhibitory effects on NADPH oxidase make it a promising candidate for therapeutic interventions in conditions associated with excessive ROS production.