For research use only. Not for therapeutic Use.
Phrixotoxin-1 TFA (Cat No.: I040202) is a potent neurotoxin derived from the venom of the Phrixotrix hirtus spider. It primarily acts by blocking voltage-gated sodium channels, leading to prolonged depolarization and inhibition of neuronal firing. This compound has garnered attention for its potential in researching pain mechanisms and as a tool for studying ion channel functions. Phrixotoxin-1 TFA is often used in experimental settings, particularly in neuroscience research, to explore the effects of sodium channel inhibition on nerve signal transmission.
| Molecular Formula | C156H240N44O37S7.xC2HF3O2 |
| Purity | ≥95% |
| Reference | [1]. Benjamin Chagot, et al. Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus. Protein Sci. 2004, 13, 5. [2]. Grit Schaarschmidt, et al. Characterization of Voltage-Gated Potassium Channels in Human Neural Progenitor Cells. PLoS One. 2009, 4, 7. |
