For research use only. Not for therapeutic Use.
Phthalocyanine (Cat.No:I008756) is an intensely blue-green-coloured aromatic macrocyclic compound that is widely used in dyeing. Phthalocyanine can be used as an agent for Photodynamic Therapy and Imaging. Phthalocyanines form coordination complexes with most elements of the periodic table. These complexes are also intensely colored and also are used as dyes or pigments.
| Catalog Number | I008756 |
| CAS Number | 574-93-6 |
| Synonyms | Phthalocyanine;phthalocyanine |
| Molecular Formula | C32H18N8 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| InChI | InChI=1S/C32H18N8/c1-2-10-18-17(9-1)25-33-26(18)38-28-21-13-5-6-14-22(21)30(35-28)40-32-24-16-8-7-15-23(24)31(36-32)39-29-20-12-4-3-11-19(20)27(34-29)37-25/h1-16H,(H2,33,34,35,36,37,38,39,40) |
| InChIKey | IEQIEDJGQAUEQZ-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C3=NC4=C5C=CC=CC5=C(N4)N=C6C7=CC=CC=C7C(=N6)N=C8C9=CC=CC=C9C(=N8)N=C2N3 |
| Reference | </br>1:Modes of Cell Death Induced by Photodynamic Therapy Using Zinc Phthalocyanine in Lung Cancer Cells Grown as a Monolayer and Three-Dimensional Multicellular Spheroids. Manoto SL, Houreld N, Hodgkinson N, Abrahamse H.Molecules. 2017 May 16;22(5). pii: E791. doi: 10.3390/molecules22050791. PMID: 28509858 Free Article</br>2:Exploiting biosynthetic gold nanoparticles for improving the aqueous solubility of metal-free phthalocyanine as biocompatible PDT agent. Alexeree SMI, Sliem MA, El-Balshy RM, Amin RM, Harith MA.Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:727-734. doi: 10.1016/j.msec.2017.03.129. Epub 2017 Mar 18. PMID: 28482583 </br>3:Template Effect of the Graphene Moiré Lattice on Phthalocyanine Assembly. Néel N, Kröger J.Molecules. 2017 May 3;22(5). pii: E731. doi: 10.3390/molecules22050731. PMID: 28467367 Free Article</br>4:Novel Multinuclear Phthalocyanine-fused Molecular Nanoarrays. Synthesis, Spectroscopy, and Semiconducting Property. Jiang J, Shang H, Xue Z, Wang K, Liu H.Chemistry. 2017 May 2. doi: 10.1002/chem.201700291. [Epub ahead of print] PMID: 28466577 </br>5:Antimicrobial and anticancer photodynamic activity of a phthalocyanine photosensitizer with N-methyl morpholiniumethoxy substituents in non-peripheral positions. Dlugaszewska J, Szczolko W, Koczorowski T, Skupin-Mrugalska P, Teubert A, Konopka K, Kucinska M, Murias M, Düzgüneş N, Mielcarek J, Goslinski T.J Inorg Biochem. 2017 Apr 8;172:67-79. doi: 10.1016/j.jinorgbio.2017.04.009. [Epub ahead of print] PMID: 28433834 </br>6:Phototoxic action of a zinc(II) phthalocyanine encapsulated into poloxamine polymeric micelles in 2D and 3D colon carcinoma cell cultures. Chiarante N, García Vior MC, Awruch J, Marino J, Roguin LP.J Photochem Photobiol B. 2017 Apr 11;170:140-151. doi: 10.1016/j.jphotobiol.2017.04.009. [Epub ahead of print] PMID: 28432944 </br>7:Microwave-Mediated Synthesis of Bulky Lanthanide Porphyrin-Phthalocyanine Triple-Deckers: Electrochemical and Magnetic Properties. Jin HG, Jiang X, Kühne IA, Clair S, Monnier V, Chendo C, Novitchi G, Powell AK, Kadish KM, Balaban TS.Inorg Chem. 2017 May 1;56(9):4864-4873. doi: 10.1021/acs.inorgchem.6b03056. Epub 2017 Apr 13. PMID: 28406618 </br>8:Effects of orientation at the phthalocyanine-CdSe interface on the electron transfer characteristics. Golovanov VV, Nazarchuk BV, Golovanova VV, Tkachenko NV, Rantala TT.Phys Chem Chem Phys. 2017 Apr 19;19(16):10511-10517. doi: 10.1039/c7cp00833c. PMID: 28387404 </br>9:A light harvesting perylene derivative – zinc phthalocyanine complex in water: spectroscopic and thermodynamic studies. El-Refaey A, Shaban SY, El-Kemary M, El-Khouly ME.Photochem Photobiol Sci. 2017 Apr 5. doi: 10.1039/c7pp00055c. [Epub ahead of print] PMID: 28379265 </br>10:Investigation of in vitro PDT activities of zinc phthalocyanine immobilised TiO<sub>2</sub> nanoparticles. Yurt F, Ince M, Colak SG, Ocakoglu K, Er O, Soylu HM, Gunduz C, Avci CB, Kurt CC.Int J Pharm. 2017 May 30;524(1-2):467-474. doi: 10.1016/j.ijpharm.2017.03.050. Epub 2017 Mar 29. PMID: 28365390 |
