PI4KIIIbeta-IN-10

• CAT Number: I002427
• CAS Number: 1881233-39-1
• Molecular Formula: C22H25N3O5S2
• Molecular Weight: 475.58
• Purity: ≥95%
• Target: PI4K
• Solubility: DMSO: ＞ 30 mg/mL
• Storage: Store at -20C
• IC50: 3.6 nM
• IUPAC Name: N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
• InChI: InChI=1S/C22H25N3O5S2/c1-13-19(31-21(23-13)24-20(27)22(2,3)4)14-6-11-17(30-5)18(12-14)32(28,29)25-15-7-9-16(26)10-8-15/h6-12,25-26H,1-5H3,(H,23,24,27)
• InChIKey: PLUYFBRIGUAKBR-UHFFFAOYSA-N
• SMILES: CC1=C(SC(=N1)NC(=O)C(C)(C)C)C2=CC(=C(C=C2)OC)S(=O)(=O)NC3=CC=C(C=C3)O

PI4KIIIbeta-IN-10（Cat No.:I002427）is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ), an enzyme involved in regulating cellular lipid signaling and membrane trafficking. By inhibiting PI4KIIIβ, this compound disrupts the synthesis of phosphatidylinositol-4-phosphate, a key lipid that plays a crucial role in the function of various cellular processes, including vesicle trafficking, endocytosis, and intracellular signaling. PI4KIIIβ-IN-10 is being studied for its potential therapeutic applications in cancer, viral infections, and other diseases linked to dysregulated lipid signaling.