Piboserod

• CAT Number: I001904
• CAS Number: 152811-62-6
• Molecular Formula: C22H31N3O2
• Molecular Weight: 369.50
• Purity: ≥95%
• Synonyms: Piboserod; SB 207266
• Target: Neuronal Signaling
• Solubility: DMSO: ≥ 36 mg/mL
• Storage: -20°C
• IUPAC Name: N-[(1-butylpiperidin-4-yl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
• InChI: InChI=1S/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)
• InChIKey: KVCSJPATKXABRQ-UHFFFAOYSA-N
• SMILES: CCCCN1CCC(CC1)CNC(=O)C2=C3N(CCCO3)C4=CC=CC=C42

Piboserod（Cat No.:I001904）is a selective 5-HT3 receptor antagonist that was investigated for its potential therapeutic applications in gastrointestinal disorders, particularly in the treatment of irritable bowel syndrome (IBS). By blocking the 5-HT3 receptors, Piboserod helps modulate gastrointestinal motility and reduce symptoms like pain, bloating, and diarrhea associated with IBS. It may also have antiemetic properties, potentially useful for controlling nausea and vomiting. Despite showing promise in preclinical and early clinical studies, Piboserod was eventually discontinued from development due to safety concerns, and further research is needed to evaluate its full therapeutic potential.