For research use only. Not for therapeutic Use.
piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage[1].
| Catalog Number | I043671 |
| CAS Number | 2418049-54-2 |
| Synonyms | (2,6-difluorophenyl)-[1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]diazene |
| Molecular Formula | C17H10F6N4 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H10F6N4/c18-12-4-1-3-11(17(21,22)23)10(12)9-27-8-7-15(26-27)24-25-16-13(19)5-2-6-14(16)20/h1-8H,9H2 |
| InChIKey | TXWNZTPRPAPHSE-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)F)CN2C=CC(=N2)N=NC3=C(C=CC=C3F)F)C(F)(F)F |
| Reference | [1]. Yang X, et al. Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles. J Am Chem Soc. 2020 May 20;142(20):9460-9470. |
