PIK-108

• CAT Number: I008759
• CAS Number: 901398-68-3
• Molecular Formula: C22H24N2O3
• Molecular Weight: 364.45
• Purity: ≥95%
• Synonyms: PIK-108; PIK 108; PIK108.;(S)-6-methyl-2-morpholino-8-(1-(phenylamino)ethyl)-4H-chromen-4-one
• Target: PI3K
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: 8-(1-anilinoethyl)-6-methyl-2-morpholin-4-ylchromen-4-one
• InChI: InChI=1S/C22H24N2O3/c1-15-12-18(16(2)23-17-6-4-3-5-7-17)22-19(13-15)20(25)14-21(27-22)24-8-10-26-11-9-24/h3-7,12-14,16,23H,8-11H2,1-2H3
• InChIKey: VRCXIJAYLCUSHC-UHFFFAOYSA-N
• SMILES: CC1=CC2=C(C(=C1)C(C)NC3=CC=CC=C3)OC(=CC2=O)N4CCOCC4

PIK-108（Cat No.:I008759）is a selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzyme, specifically targeting the PI3Kδ isoform. The PI3K signaling pathway plays a critical role in cell growth, survival, and immune responses. By inhibiting PI3Kδ, PIK-108 has potential therapeutic applications in conditions such as cancer, autoimmune diseases, and chronic inflammation, where the pathway is often dysregulated. Research into PIK-108 is ongoing, focusing on its effectiveness as a targeted therapy for diseases associated with PI3Kδ activation, with a particular emphasis on safety and pharmacological properties.