For research use only. Not for therapeutic Use.
Pimonidazole hydrochloride (Cat.No:I017996) is a hypoxia marker commonly used in cancer research. It forms stable adducts under hypoxic conditions, allowing for the detection and visualization of low-oxygen regions in tissues. Pimonidazole hydrochloride finds applications in studying tumor hypoxia, evaluating treatment response, and developing hypoxia-targeted therapies.
| Catalog Number | I017996 |
| CAS Number | 70132-51-3 |
| Molecular Formula | C₁₁H₁₉ClN₄O₃ |
| Purity | ≥95% |
| Reference | [1]. Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71(2):270-7.<br>[2]. Masaki Y, et al. Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent “Pimonidazole” in Hypoxia. PLoS One. 2016 Aug 31;11(8):e0161639.<br>[3]. Kristina Y Aguilera, et al. Hypoxia Studies with Pimonidazole in vivo. Bio Protoc<br>[4]. Stephanie M Evans, et al. Molecular probes for imaging of hypoxia in the retina. Bioconjug Chem. . 2014 Nov 19;25(11):2030-7.<br>[5]. Stephanie M Evans, et al. Molecular probes for imaging of hypoxia in the retina. Bioconjug Chem. . 2014 Nov 19;25(11):2030-7. |
