Pin1 modulator 1

• CAT Number: I040454
• CAS Number: 301688-74-4
• Molecular Formula: C18H15NO3S2
• Molecular Weight: 357.45
• Purity: ≥95%
• Synonyms: 4-[(5E)-5-(naphthalen-1-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid
• InChI: InChI=1S/C18H15NO3S2/c20-16(21)9-4-10-19-17(22)15(24-18(19)23)11-13-7-3-6-12-5-1-2-8-14(12)13/h1-3,5-8,11H,4,9-10H2,(H,20,21)/b15-11+
• InChIKey: NMYDPSCPARBVHD-RVDMUPIBSA-N
• SMILES: C1=CC=C2C(=C1)C=CC=C2C=C3C(=O)N(C(=S)S3)CCCC(=O)O

Pin1 modulator 1 (compound IIb-219) is a modulator that specifically targets β-Catenin and inhibits the Wnt pathway. Pin1 modulator 1 can be used in the study of Wnt-mediated related diseases, such as cancer[1].

Reference

[1]. Ramanuj Dasgupta, et al. Oxazole and thiazole compounds as b-catenin modulators and uses thereof. Patent WO2009097113A2.