Pinaverium-d4 Bromide

• CAT Number: R007461
• CAS Number: NA
• Molecular Formula: C₂₆H₃₇D₄Br₂NO₄
• Molecular Weight: 595.44
• Purity: ≥95%
• Synonyms: 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]-hept-2-yl)ethoxy]ethyl]morpholinium-d4 Bromide; LAT-1717-d4; Dicetel-d4; ?
• Storage: -20°C
• IUPAC Name: 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[1,1,2,2-tetradeuterio-2-[2-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium;bromide
• InChI: InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1/i8D2,12D2
• InChIKey: IKGXLCMLVINENI-WVYYIIHHSA-M
• SMILES: [2H]C([2H])(C([2H])([2H])OCCC1CCC2CC1C2(C)C)[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC.[Br-]

Pinaverium-d4 Bromide is a deuterated form of pinaverium bromide, where four hydrogen atoms are replaced with deuterium. Pinaverium bromide is a calcium channel blocker commonly used to treat gastrointestinal disorders such as irritable bowel syndrome (IBS). The deuterium labeling in Pinaverium-d4 Bromide enhances the stability and precision in pharmacokinetic studies, particularly when using mass spectrometry for detailed analysis of drug absorption, distribution, metabolism, and excretion (ADME). This compound is valuable in pharmaceutical research for understanding the drug’s behavior in the body, aiding in the development of more effective treatments for gastrointestinal conditions while providing reliable and consistent data for clinical studies.