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42438-89-1-Pinostilbene Pinostilbene

Pinostilbene

For research use only. Not for therapeutic Use.

  • CAT Number: R006680
  • CAS Number: 42438-89-1
  • Molecular Formula: C15H14O3
  • Molecular Weight: 242.274
  • Purity: ≥95%
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Related Small Molecules: 20α-Hydroxymethylpregna-1,4-dien-3-one     2-Bromo-4-phenylphenol     Diallyl bisphenol A    

Pinostilbene (CAS&nbsp;42438-89-1) is a stable, monomethoxylated resveratrol derivative with enhanced bioavailability compared to resveratrol. At 0.1-<wbr />10 &mu;M pinostilbene reduces neurotoxicity in SH-<wbr />SY5Y cells induced by the parkinsonian mimetic 6-<wbr />hydroxydopamine and scavenges 2,2-<wbr />diphenyl-<wbr />1-<wbr />picrylhydrazyl radicals with an IC<sub>50</sub> value of 47.1 &mu;M.


Catalog Number R006680
CAS Number 42438-89-1
Synonyms

3-[(1E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxy-phenol

Molecular Formula C15H14O3
Purity ≥95%
Target Drug Metabolite
Storage -20°C
IUPAC Name 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenol
InChI InChI=1S/C15H14O3/c1-18-15-9-12(8-14(17)10-15)3-2-11-4-6-13(16)7-5-11/h2-10,16-17H,1H3/b3-2+
InChIKey KUWZXOMQXYWKBS-NSCUHMNNSA-N
SMILES COC1=CC(=CC(=C1)O)C=CC2=CC=C(C=C2)O
Reference

<p>
<span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.<span class="authors" data-text="Wilson, M.A., Rimando, A.M., and Wolkow, C.A." style="box-sizing: border-box;">Wilson, M.A., Rimando, A.M., and Wolkow, C.A.</span><span class="title" data-text="Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans" style="box-sizing: border-box;">&nbsp;<span style="box-sizing: border-box;"><span class="scientificMarkup" style="box-sizing: border-box;">Methoxylation enhances stilbene bioactivity in&nbsp;<span class="species" style="box-sizing: border-box;">Caenorhabditis elegans</span></span></span>.</span><span class="text-lato-light-italic" style="box-sizing: border-box;">&nbsp;BMC Pharmacology</span><span class="number" style="box-sizing: border-box;">&nbsp;8(15),</span><span class="year" style="box-sizing: border-box;">&nbsp;(2008)</span>.<br />
2.<span class="authors" data-text="Chao, J., Li, H., Cheng, K.W., et al." style="box-sizing: border-box;">Chao, J., Li, H., Cheng, K.W.,&nbsp;<span class="foreign" style="box-sizing: border-box;">et al</span>.</span><span class="title" data-text="Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells" style="box-sizing: border-box;">&nbsp;<span style="box-sizing: border-box;"><span class="scientificMarkup" style="box-sizing: border-box;">Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-<wbr style="box-sizing: border-box;" />hydroxydopamine-<wbr style="box-sizing: border-box;" />induced neurotoxicity in SH-<wbr style="box-sizing: border-box;" />SY5Y cells</span></span>.</span><span class="text-lato-light-italic" style="box-sizing: border-box;">&nbsp;Journal of Nutritional Biochemistry</span><span class="number" style="box-sizing: border-box;">&nbsp;21(6),</span><span class="pagerange" style="box-sizing: border-box;">&nbsp;482-489</span><span class="year" style="box-sizing: border-box;">&nbsp;(2010)</span>.</span></span></p>

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