pinosylvin

For research use only. Not for therapeutic Use.

  • CAT Number: M069342
  • CAS Number: 102-61-4
  • Molecular Formula: C14H12O2
  • Molecular Weight: 212.248
  • Purity: ≥95%
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pinosylvin (CAS&nbsp;102-61-4)<span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;is a pre-infectious stilbenoid toxin that is synthetized in plants during fungal infections, ozone induced stress and physical damage for example. It is a fungitoxin protecting the wood from fungal infection. It is present in the heartwood of Pinaceae and also found in Gnetum cleistostachyum.</span></span></span></span>


Catalog Number M069342
CAS Number 102-61-4
Molecular Formula C14H12O2
Purity ≥95%
Storage Store at RT
Overview of Clinical Research

<span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;">pinosylvin is a&nbsp;<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">RNA-directed DNA polymerase inhibitor used to treat&nbsp;</span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">HIV infections.</span></span></span></span>

IUPAC Name 5-[(E)-2-phenylethenyl]benzene-1,3-diol
InChI InChI=1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+
InChIKey YCVPRTHEGLPYPB-VOTSOKGWSA-N
SMILES C1=CC=C(C=C1)C=CC2=CC(=CC(=C2)O)O
Reference

<span style="font-family:arial,helvetica,sans-serif;"><span style="color:#000000;"><span style="font-size:12px;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">1. Hovelstad H, Leirset I, Oyaas K, Fiksdahl A. Screening analyses of pinosylvin stilbenes, resin acids and lignans in Norwegian conifers. Molecules. 2006 Jan 31;11(1):103-14. doi: 10.3390/11010103. PMID: 17962750; PMCID: PMC6148674.</span><br />
<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">2. Lee SK, Lee HJ, Min HY, Park EJ, Lee KM, Ahn YH, Cho YJ, Pyee JH. Antibacterial and antifungal activity of pinosylvin, a constituent of pine. Fitoterapia. 2005 Mar;76(2):258-60. doi: 10.1016/j.fitote.2004.12.004. PMID: 15752644.</span><br />
<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">3. Yao CS, Lin M, Liu X, Wang YH. Stilbene derivatives from Gnetum cleistostachyum. J Asian Nat Prod Res. 2005 Apr;7(2):131-7. doi: 10.1080/10286020310001625102. PMID: 15621615.<br />
<span style="font-variant-ligatures: normal;">4. Roupe KA, Y&aacute;&ntilde;ez JA, Teng XW, Davies NM. Pharmacokinetics of selected stilbenes: rhapontigenin, piceatannol and pinosylvin in rats. J Pharm Pharmacol. 2006 Nov;58(11):1443-50. doi: 10.1211/jpp.58.11.0004. PMID: 17132206.</span><br />
<span style="font-variant-ligatures: normal;">5. Schmitt B, H&ouml;lscher D, Schneider B. Variability of phenylpropanoid precursors in the biosynthesis of phenylphenalenones in Anigozanthos preissii. Phytochemistry. 2000 Feb;53(3):331-7. doi: 10.1016/s0031-9422(99)00544-0. PMID: 10703053.<br />
<span style="font-variant-ligatures: normal;">6. Kita T, Imai S, Sawada H, Kumagai H, Seto H. The biosynthetic pathway of curcuminoid in turmeric (Curcuma longa) as revealed by 13C-labeled precursors. Biosci Biotechnol Biochem. 2008 Jul;72(7):1789-98. doi: 10.1271/bbb.80075. Epub 2008 Jul 7. PMID: 18603793.</span></span></span></span></span></span>

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