For research use only. Not for therapeutic Use.
Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].
| Catalog Number | I008771 |
| CAS Number | 2167-85-3 |
| Synonyms | 2-(2-piperidin-1-ylethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate |
| Molecular Formula | C21H25N3O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C21H25N3O3S/c25-21(27-16-15-26-14-13-23-11-4-1-5-12-23)24-17-7-2-3-8-18(17)28-19-9-6-10-22-20(19)24/h2-3,6-10H,1,4-5,11-16H2 |
| InChIKey | DTVJXCOMJLLMAK-UHFFFAOYSA-N |
| SMILES | C1CCN(CC1)CCOCCOC(=O)N2C3=CC=CC=C3SC4=C2N=CC=C4 |
| Reference | [1]. Squires RF, et, al. Antidepressants and metabolites that block GABAA receptors coupled to 35S-t-butylbicyclophosphorothionate binding sites in rat brain. Brain Res. 1988 Feb 16;441(1-2):15-22. |
