Piperaquine phosphate

• CAT Number: M002788
• CAS Number: 4085-31-8
• Molecular Formula: C29H32Cl2N6
• Molecular Weight: 535.51
• Purity: ≥95%
• Synonyms: 1,3-bis[1-(7-chloro-4-quinolyl)-4/’-piperazinyl]propane tetraphosphate tetrahydrate;Piperaquine phosphate CP2000;PIRERAQUINE PHOSPHATE;4,4/’-(1,3-Propanediydi-4,1-piper-azinediyl)bis[7-chloroquinoline];
• Target: HIV
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
• InChI: InChI=1S/C29H32Cl2N6/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29/h2-9,20-21H,1,10-19H2
• InChIKey: UCRHFBCYFMIWHC-UHFFFAOYSA-N
• SMILES: C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl

Piperaquine Phosphate（Cat No.:M002788）is a long-acting antimalarial drug widely used in combination therapies for the treatment of Plasmodium falciparum and Plasmodium vivax malaria. It belongs to the bisquinoline class and works by interfering with heme detoxification in the parasite, leading to its death. Piperaquine’s extended half-life enhances its efficacy and provides a protective effect against reinfection. It is commonly paired with dihydroartemisinin to form artemisinin-based combination therapies (ACTs), ensuring potent and synergistic antimalarial action. Piperaquine remains a critical component in global malaria control strategies.