For research use only. Not for therapeutic Use.
Piperazine-Erastin (Cat.No:I034783) is a chemical compound designed to selectively induce ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent lipid peroxidation. By targeting and inhibiting the system Xc- cystine/glutamate antiporter, Piperazine-Erastin has shown potential in cancer therapy by inducing ferroptosis-mediated cell death in cancer cells. Further research is ongoing to explore its therapeutic applications.
| Catalog Number | I034783 |
| CAS Number | 1538593-71-3 |
| Synonyms | Piperazine-Erastin; Piperazine Erastin; PiperazineErastin; |
| Molecular Formula | C35H41ClN6O4 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(piperazin-1-ylmethyl)-2-propan-2-yloxyphenyl]quinazolin-4-one |
| InChI | InChI=1S/C35H41ClN6O4/c1-25(2)46-32-12-7-26(22-39-15-13-37-14-16-39)21-31(32)42-33(38-30-6-4-3-5-29(30)35(42)44)23-40-17-19-41(20-18-40)34(43)24-45-28-10-8-27(36)9-11-28/h3-12,21,25,37H,13-20,22-24H2,1-2H3 |
| InChIKey | XGKULGPEBBYKCA-UHFFFAOYSA-N |
| SMILES | O=C1N(C2=CC(CN3CCNCC3)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6 |
