For research use only. Not for therapeutic Use.
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4].
| Catalog Number | R067529 |
| CAS Number | 5950-12-9 |
| Synonyms | (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide |
| Molecular Formula | C16H19NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H19NO3/c1-12(2)10-17-16(18)6-4-3-5-13-7-8-14-15(9-13)20-11-19-14/h3-9,12H,10-11H2,1-2H3,(H,17,18)/b5-3+,6-4+ |
| InChIKey | WHAAPCGHVWVUEX-GGWOSOGESA-N |
| SMILES | CC(C)CNC(=O)C=CC=CC1=CC2=C(C=C1)OCO2 |
| Reference | [1]. Bezerra DP, et, al. In vivo growth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from the Piper species. J Appl Toxicol. 2008 Jul; 28(5): 599-607. [2]. Yang T, et, al. Piperlonguminine is neuroprotective in experimental rat stroke. Int Immunopharmacol. 2014 Dec; 23(2): 447-51. [3]. Marques JV, et, al. Antifungal amides from Piper scutifolium and Piper hoffmanseggianum. J Nat Prod. 2007 Dec; 70(12):2036-9. [4]. Chy MNU, et, al. Antibacterial, anthelmintic, and analgesic activities of Piper sylvaticum (Roxb.) leaves and in silico molecular docking and PASS prediction studies of its isolated compounds. J Complement Integr Med. 2019 Aug 22;16(4). |
