For research use only. Not for therapeutic Use.
Pirbuterol (Cat. No: I008777) is a short-acting β2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma.
| Catalog Number | I008777 |
| CAS Number | 38677-81-5 |
| Synonyms | Pirbuterol; Pirbuterolum; Pirbuterolum [INN-Latin]; CP-24,314-14.;Ethanol, 2-tert-butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)- |
| Molecular Formula | C12H20N2O3 |
| Purity | ≥95% |
| Target | β2 adrenoreceptor agonist |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term , or -20°C for long term. |
| IUPAC Name | 6-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)pyridin-3-ol |
| InChI | InChI=1S/C12H20N2O3/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8/h4-5,11,13,15-17H,6-7H2,1-3H3 |
| InChIKey | VQDBNKDJNJQRDG-UHFFFAOYSA-N |
| SMILES | CC(C)(C)NCC(C1=NC(=C(C=C1)O)CO)O |
| Reference | </br>1:Salbutamol, terbutaline and pirbuterol allergy in an asthmatic patient. Bonniaud P, Favrolt N, Collet E, Dumas JP, Guilloux L, Pauli G, Camus P.Allergy. 2007 Oct;62(10):1219-20. No abstract available. PMID: 17845596 Free Article</br>2:Use of a hand-held, metered-dose aerosol delivery device to administer pirbuterol acetate to horses with /’heaves/’. Derksen FJ, Olszewski M, Robinson NE, Berney C, Lloyd JW, Hakala J, Matson C, Ruth D.Equine Vet J. 1996 Jul;28(4):306-10. PMID: 8818596 </br>3:Nonbronchodilator effects of pirbuterol and ipratropium in chronic obstructive pulmonary disease. Ashutosh K, Dev G, Steele D.Chest. 1995 Jan;107(1):173-8. PMID: 7813271 </br>4:Double-blind, clinical efficacy study comparing 400 micrograms of pirbuterol versus placebo delivered by a breath-actuated aerosol inhaler. Tinkelman DG, Vanden Burgt JA, Ekholm BP.J Asthma. 1994;31(3):187-92. PMID: 7910819 </br>5:Maximum bronchodilator effect of pirbuterol and procaterol administered as sprays with and without an aerochamber. Solé D, Villalba SR, Sestelo MR, Scalabrin DM, Soares FJ, Naspitz CK.Rev Paul Med. 1993 May-Jun;111(3):397-402. PMID: 8108632 </br>6:Ease-of-use study of pirbuterol acetate in the Autohaler actuator in three countries: the United States, Germany, and France. Bronsky EA, Debelic M, Pujet JC, Hahn M.J Asthma. 1993;30(6):439-43. PMID: 8244913 </br>7:Aerosol pirbuterol: bronchodilator activity and side effects in ponies with recurrent airway obstruction (heaves). Derksen FJ, Robinson NE, Berney CE.Equine Vet J. 1992 Mar;24(2):107-12. PMID: 1582387 </br>8:[Pirbuterol: a new beta 2-sympathomimetic agent. An open multicenter study]. Dry J, Pradalier A, Michel FB, Pariente R, Boutin C.Therapie. 1991 May-Jun;46(3):253-4. French. No abstract available. PMID: 1792660 </br>9:Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler. Völkl KP, Kroll VM, Wiesemann HG, Schneider B.Arzneimittelforschung. 1991 May;41(5):533-6. PMID: 1680327 </br>10:Ocular hypotensive activity of pirbuterol eye drops in rabbits. Bonomi L, Perfetti S, Bellucci R, De Franco I.J Ocul Pharmacol. 1991 Fall;7(3):191-4. PMID: 1686050 |
