Pirenzepine-d8 dihydrochloride

• CAT Number: S000468
• Molecular Formula: C19H15D8Cl2N5O2
• Molecular Weight: 432.37
• Purity: ≥95%
• IUPAC Name: 11-[2-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
• InChI: InChI=1S/C19H21N5O2/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24/h2-8H,9-13H2,1H3,(H,21,26)/i9D2,10D2,11D2,12D2
• InChIKey: RMHMFHUVIITRHF-PMCMNDOISA-N
• SMILES: CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4

Pirenzepine-d8 dihydrochloride（Cat No.:S000468） is a deuterated form of pirenzepine, where eight hydrogen atoms are replaced with deuterium. This variant is used in scientific research to investigate how the addition of deuterium affects the drug’s metabolic stability and pharmacokinetics. Pirenzepine is an antimuscarinic agent primarily used to treat peptic ulcers by selectively blocking M1 muscarinic receptors in the stomach, reducing gastric acid secretion. The dihydrochloride form increases the solubility of the drug, improving its bioavailability.