Pirlimycin

• CAT Number: M008732
• CAS Number: 79548-73-5
• Molecular Formula: C17H31ClN2O5S
• Molecular Weight: 411.00
• Purity: ≥95%
• Synonyms: Pirlimycin;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;L-Threo-alpha-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-((((2S,4R)-4-ethyl-2-piperidinyl)carbonyl)am
• Target: Antibiotic
• Solubility: Soluble in DMSO
• Appearance: White solid
• Storage: Store at -20°C
• IUPAC Name: (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-ethylpiperidine-2-carboxamide
• InChI: InChI=1S/C17H31ClN2O5S/c1-4-9-5-6-19-10(7-9)16(24)20-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-3/h8-15,17,19,21-23H,4-7H2,1-3H3,(H,20,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1
• InChIKey: HBJOXQRURQPDEX-MHXMMLMNSA-N
• SMILES: CC[C@@H]1CCN[C@@H](C1)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl

Pirlimycin（Cat No.:M008732）is a lincosamide antibiotic used primarily in veterinary medicine to treat bovine mastitis caused by Gram-positive bacteria, including Staphylococcus and Streptococcus species. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide elongation. With its broad-spectrum antibacterial activity and targeted efficacy, pirlimycin is administered as an intramammary infusion, offering a practical solution for dairy cattle infections. Its favorable pharmacokinetics and low resistance profile enhance its effectiveness, making pirlimycin a valuable tool in veterinary antibiotic therapies and mastitis management strategies.

Reference

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