For research use only. Not for therapeutic Use.
Pirlindole is a reversible inhibitor of monoamine oxidase A (RIMA) which was developed and is used in Russia as an antidepressant. It is structurally and pharmacologically related to metralindole. Pirlindole is approved in some European and non-European countries for the treatment of depression. Pirlindole has an absolute bioavailability of between 20 and 30% due to an extensive first-pass effect. Orally, the Tmax varies between 2.5 and 6 h in the rat and 0.8 and 2 h in the dog.
| Catalog Number | I011993 |
| CAS Number | 60762-57-4 |
| Synonyms | Pirlindole. Lifril, Pyrazidol,;2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole |
| Molecular Formula | C15H18N2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | Store at 0-8 °C |
| InChI | InChI=1S/C15H18N2/c1-10-5-6-14-12(9-10)11-3-2-4-13-15(11)17(14)8-7-16-13/h5-6,9,13,16H,2-4,7-8H2,1H3 |
| InChIKey | IWVRVEIKCBFZNF-UHFFFAOYSA-N |
| SMILES | CC1=CC2=C(C=C1)N3C4=C2CCCC4NCC3 |
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