Pirogliride free base

• CAT Number: I034834
• CAS Number: 62625-18-7
• Molecular Formula: C16H22N4
• Molecular Weight: 270.38
• Purity: 98%
• Synonyms: Pirogliride Free Base; McN3495; McN 3495; McN-3495
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: N-(1-methylpyrrolidin-2-ylidene)-N'-phenylpyrrolidine-1-carboximidamide
• InChI: InChI=1S/C16H22N4/c1-19-11-7-10-15(19)18-16(20-12-5-6-13-20)17-14-8-3-2-4-9-14/h2-4,8-9H,5-7,10-13H2,1H3
• InChIKey: UFJFKQGRZLHOBO-UHFFFAOYSA-N
• SMILES: CN1CCCC1=NC(=NC2=CC=CC=C2)N3CCCC3

Pirogliride free base（Cat No.:I034834）is an antihyperglycemic agent used primarily in the treatment of type 2 diabetes. It works by improving insulin sensitivity and promoting the uptake of glucose into cells, thereby helping to regulate blood sugar levels. Pirogliride is part of a class of drugs known as thiazolidinediones (TZDs) but has a distinct chemical structure. It acts on peroxisome proliferator-activated receptors (PPARs), specifically PPAR-gamma, which play a role in glucose and lipid metabolism. Pirogliride has shown potential in reducing insulin resistance and improving glycemic control, though it may have side effects such as weight gain and fluid retention.