For research use only. Not for therapeutic Use.
Pitavastatin Calcium(Cat No.:A000464)is a potent HMG-CoA reductase inhibitor, or statin, used to lower cholesterol levels and reduce cardiovascular risk. By blocking the enzyme responsible for cholesterol synthesis in the liver, it effectively reduces LDL cholesterol and triglycerides while modestly increasing HDL cholesterol. Known for its favorable pharmacokinetic profile, pitavastatin is especially beneficial in patients with metabolic syndrome and diabetes, as it has minimal impact on glucose metabolism. It is also researched for its anti-inflammatory and plaque-stabilizing effects, supporting its role in comprehensive cardiovascular disease management.
Catalog Number | A000464 |
CAS Number | 147526-32-7 |
Synonyms | NK-104 Calcium |
Molecular Formula | [C25H24FNO4]2 • Ca |
Purity | ≥95% |
Target | HMG-CoA Reductase |
Solubility | >34.9mg/mL in DMSO |
Storage | 3 years -20C powder |
IUPAC Name | calcium;(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate |
InChI | InChI=1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1 |
InChIKey | RHGYHLPFVJEAOC-FFNUKLMVSA-L |
SMILES | C1C(C1)C2=NC3=CC=CC=C3C(=C2/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C4=CC=C(C=C4)F.C1C(C1)C2=NC3=CC=CC=C3C(=C2/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C4=CC=C(C=C4)F.[Ca+2] |