For research use only. Not for therapeutic Use.
Pitavastatin-d5 sodium, a premium pharmaceutical research compound designed for advanced lipid-lowering and cardiovascular studies. As a deuterated analog of Pitavastatin, it offers enhanced stability and improved pharmacokinetic properties. Pitavastatin-d5 sodium is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for hyperlipidemia and cardiovascular diseases. Trusted by leading laboratories, Pitavastatin-d5 sodium is your go-to solution for cutting-edge cardiovascular research. Unlock new possibilities in cholesterol management and heart disease treatment with Pitavastatin-d5 sodium, where innovation meets reliability.
| Catalog Number | S000212 |
| Molecular Formula | C25H18D5FNNaO4 |
| Purity | ≥95% |
| Target | Autophagy |
| IUPAC Name | sodium;(E,3R,5S)-7-[4-(4-fluorophenyl)-2-(1,2,2,3,3-pentadeuteriocyclopropyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate |
| InChI | InChI=1S/C25H24FNO4.Na/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1/i5D2,6D2,16D; |
| InChIKey | NBDQGOCGYHMDSJ-JVDMFWQQSA-M |
| SMILES | [2H]C1(C(C1([2H])C2=NC3=CC=CC=C3C(=C2/C=C/[C@H](C[C@H](CC(=O)[O-])O)O)C4=CC=C(C=C4)F)([2H])[2H])[2H].[Na+] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. ;Morikawa S, et al. Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase [2]. Morikawa S, et al. Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells. J Atheroscler Thromb. 2000;7(3):138-44. [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. |
