Pitolisant oxalate

• CAT Number: I003333
• CAS Number: 362665-57-4
• Molecular Formula: C19H28ClNO5
• Molecular Weight: 385.88
• Purity: ≥95%
• Synonyms: 1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine oxalate
• Target: Neuronal Signaling
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IC50: 0.16 nM (Ki value); 1.5 nM (EC50)
• IUPAC Name: 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine;oxalic acid
• InChI: InChI=1S/C17H26ClNO.C2H2O4/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19;3-1(4)2(5)6/h7-10H,1-6,11-15H2;(H,3,4)(H,5,6)
• InChIKey: OZTKSXOIWBLDBB-UHFFFAOYSA-N
• SMILES: C1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl.C(=O)(C(=O)O)O

Pitolisant oxalate（Cat No.:I003333）is a medication used primarily for the treatment of narcolepsy, a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. Pitolisant works as a selective histamine H3 receptor antagonist/inverse agonist, which increases the release of histamine in the brain, thereby promoting wakefulness and improving alertness. It has also shown potential in treating other sleep disorders and may have cognitive-enhancing effects. Unlike traditional stimulants, pitolisant has a lower risk of dependence and abuse, making it a safer option for long-term management of narcolepsy and other sleep disorders.