For research use only. Not for therapeutic Use.
Pivalophenone(CAT: I014574), also known as pivalophenone or trimethylacetylphenone, is a ketone that is widely used as an intermediate in organic synthesis and as a building block for the production of various compounds. Pivalophenone has applications in pharmaceuticals, agrochemicals, fragrances, and other industries.
| Catalog Number | I014574 |
| CAS Number | 938-16-9 |
| Synonyms | PivalopheNA; AI3-11505; AI3 11505; AI311505;1-PropaNA, 2,2-dimethyl-1-phenyl- |
| Molecular Formula | C11H14O |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| InChI | InChI=1S/C11H14O/c1-11(2,3)10(12)9-7-5-4-6-8-9/h4-8H,1-3H3 |
| InChIKey | OECPUBRNDKXFDX-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(C1=CC=CC=C1)=O |
| Reference | </br> 1: Xu W, Yoshikai N. Cobalt-catalyzed directed C-H alkenylation of pivalopheNA N-H imine with alkenyl phosphates. Beilstein J Org Chem. 2018 Mar 28;14:709-715. doi: 10.3762/bjoc.14.60. eCollection 2018. PubMed PMID: 29719569; PubMed Central PMCID: PMC5905286.</br>2: Xu W, Yoshikai N. PivalopheNA imine as a benzonitrile surrogate for directed C-H bond functionalization. Chem Sci. 2017 Aug 1;8(8):5299-5304. doi: 10.1039/c7sc01732d. Epub 2017 May 30. PubMed PMID: 28970910; PubMed Central PMCID: PMC5607892.</br>3: Ueno S, Chatani N, Kakiuchi F. Regioselective alkenylation of aromatic ketones with alkenylboronates using a RuH2(CO)(PPh3)3 catalyst via carbon-hydrogen bond cleavage. J Org Chem. 2007 Apr 27;72(9):3600-2. Epub 2007 Apr 4. PubMed PMID: 17407360.</br>4: Ueno S, Mizushima E, Chatani N, Kakiuchi F. Direct observation of the oxidative addition of the aryl carbon-oxygen bond to a ruthenium complex and consideration of the relative reactivity between aryl carbon-oxygen and aryl carbon-hydrogen bonds. J Am Chem Soc. 2006 Dec 27;128(51):16516-7. PubMed PMID: 17177397.</br>5: Kakiuchi F, Matsuura Y, Kan S, Chatani N. A RuH(2)(CO)(PPh(3))(3)-catalyzed regioselective arylation of aromatic ketones with arylboronates via carbon-hydrogen bond cleavage. J Am Chem Soc. 2005 Apr 27;127(16):5936-45. PubMed PMID: 15839693.</br>6: Chan B, Radom L. Base-catalyzed hydrogenation: rationalizing the effects of catalyst and substrate structures and solvation. J Am Chem Soc. 2005 Mar 2;127(8):2443-54. PubMed PMID: 15724999.</br></br> |
