For research use only. Not for therapeutic Use.
Pivmecillinam（Cat No.:I003169）, also known as Amdinocillin pivoxil, is an orally active prodrug of mecillinam. Mecillinam belongs to the class of extended-spectrum penicillin antibiotics and is effective against a wide range of bacterial infections. Pivmecillinam is rapidly converted to mecillinam after oral administration, allowing for convenient and efficient treatment of bacterial infections. It is particularly useful for urinary tract infections caused by susceptible bacteria. Pivmecillinam’s oral activity and the spectrum of mecillinam make it a valuable option in the management of various bacterial infections.
| Catalog Number | I003169 |
| CAS Number | 32887-03-9 |
| Molecular Formula | C21H34ClN3O5S |
| Purity | ≥95% |
| Target | Bacterial |
| Solubility | DMSO: ＞ 34 mg/mL |
| Storage | 2-8°C |
| IUPAC Name | 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrochloride |
| InChI | InChI=1S/C21H33N3O5S.ClH/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23;/h12,14-15,17H,6-11,13H2,1-5H3;1H/t14-,15+,17-;/m1./s1 |
| InChIKey | UHPXMYLONAGUPC-WKLLBTDKSA-N |
| SMILES | CC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)OCOC(=O)C(C)(C)C)C.Cl |
| Reference | </br>1:[Clinical study of pivmecillinam hydrochloride in lower urinary tract infections in pregnant women. Apropos of 44 cases]. Henrion R, Vige P.Rev Fr Gynecol Obstet. 1987 Dec;82(12):761-4. French. No abstract available. PMID: 3324273 </br>2:Pharmacokinetics of pivmecillinam hydrochloride in pregnant and non-pregnant women. Kjer JJ, Ottesen B.Acta Pharmacol Toxicol (Copenh). 1986 Nov;59(5):430-1. No abstract available. PMID: 3811971 </br>3:Stability-indicating assay for pivmecillinam hydrochloride and pivmecillinam hydrochloride capsules. Hagel RB, Waysek EH.J Chromatogr. 1979 Oct 19;178(1):97-14. PMID: 231046 </br>4:Urinary excretion of mecillinam by volunteers receiving film-coated tablets of pivmecillinam hydrochloride. Anderson JD, Adams MA.Chemotherapy. 1979;25(1):1-4. PMID: 217572 |
