For research use only. Not for therapeutic Use.
Pizuglanstat (compound 3) is a prostaglandin D synthase inhibitor with an IC50 of 76 nM for human hematopoietic prostaglandin D synthases (H-PGDS). Pizuglanstat can be used for myodegenerative disease research, such as muscular dystrophy[1].
| Catalog Number | I034852 |
| CAS Number | 1244967-98-3 |
| Synonyms | 4-(1-methylpyrrole-2-carbonyl)-N-[4-[4-(morpholine-4-carbonyl)piperidin-1-yl]phenyl]piperazine-1-carboxamide |
| Molecular Formula | C27H36N6O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H36N6O4/c1-29-10-2-3-24(29)26(35)31-13-15-33(16-14-31)27(36)28-22-4-6-23(7-5-22)30-11-8-21(9-12-30)25(34)32-17-19-37-20-18-32/h2-7,10,21H,8-9,11-20H2,1H3,(H,28,36) |
| InChIKey | ZNFJGCDCPYTEKF-UHFFFAOYSA-N |
| SMILES | CN1C=CC=C1C(=O)N2CCN(CC2)C(=O)NC3=CC=C(C=C3)N4CCC(CC4)C(=O)N5CCOCC5 |
| Reference | [1]. Yoshihiro Urade, et al. Piperazine compound capable of inhibiting prostaglandin D synthase. US8865714B2. |
