PJ-34 hydrochloride

• CAT Number: I003256
• CAS Number: 344458-15-7
• Molecular Formula: C₁₇H₁₇N₃O₂.HCl
• Molecular Weight: 331.81
• Purity: ≥95%
• Synonyms: 2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide;hydrochloride
• Target: Epigenetics
• Solubility: DMSO > 35 mg/ml
• Storage: 3 years -20C powder
• IC50: 20 nM(EC50)[1]
• InChI: InChI=1S/C17H17N3O2.ClH.H2O/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H;1H2
• InChIKey: YCALIZUKAFUQCH-UHFFFAOYSA-N
• SMILES: CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.O.Cl

PJ-34 Hydrochloride(CAT: I003256) is a potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP), a key enzyme involved in DNA repair processes. By inhibiting PARP activity, this compound is widely used in research focused on apoptosis, cancer biology, and neurodegenerative diseases. PJ-34 Hydrochloride exhibits high water solubility and bioavailability, making it suitable for in vitro and in vivo studies. Its ability to modulate DNA repair pathways makes it a critical tool for exploring therapeutic strategies targeting cancer and other diseases associated with DNA damage. With consistent performance and high purity, it supports advanced pharmaceutical and biochemical research applications.