PKA-IN-1

• CAT Number: R002367
• CAS Number: 179985-52-5
• Molecular Formula: C13H11N3O
• Molecular Weight: 225.25
• Purity: ≥95%
• Synonyms: N-(4-cyano-3-methylisoquinolin-1-yl)acetamide
• InChI: InChI=1S/C13H11N3O/c1-8-12(7-14)10-5-3-4-6-11(10)13(15-8)16-9(2)17/h3-6H,1-2H3,(H,15,16,17)
• InChIKey: SRNACQXBALMDDC-UHFFFAOYSA-N
• SMILES: CC1=C(C2=CC=CC=C2C(=N1)NC(=O)C)C#N

PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1].

Reference

[1]. Z X Lu, et al. Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivative. Biol Chem Hoppe Seyler. 1996 Jun;377(6):373-8
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